Before acting, McCoy-Misick began her career as a model doing fashion shows in churches and high schools in her native Chicago. She made her acting debut as the lead in Reasons, an independent film directed by Monty Ross. She also had the lead role in the film The Players Club, directed and written by Ice Cube.; and has film credits in The Wood, opposite Omar Epps, as well as Love the Way, Rhapsody, All About You, and Go for Broke. In 2003, McCoy starred as Neesee James in the CW sitcom All of Us. She played Robert Sr.'s (Duane Martin) self-absorbed ex-wife and the mother of their 6-year-old son, Bobby, Jr. The series ended in 2007.
